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2′-Deoxyadenosine 5′-monophosphate disodium

CAS No. 2922-74-9

2′-Deoxyadenosine 5′-monophosphate disodium( —— )

Catalog No. M28292 CAS No. 2922-74-9

2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2′-Deoxyadenosine 5′-monophosphate disodium
  • Note
    Research use only, not for human use.
  • Brief Description
    2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
  • Description
    2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage.(In Vitro):2′-Deoxyadenosine 5′-monophosphate (dAMP) is incorporated into Caco-2 cells in a time-dependent manner. The uptake of 2′-Deoxyadenosine 5′-monophosphate is increased with a drop in pH, suggesting that 2′-Deoxyadenosine 5′-monophosphate transport activity might be linked to the protons. 2′-Deoxyadenosine 5′-monophosphate uptake by Caco-2 cells is pH- and Na+-dependent.
  • In Vitro
    2′-Deoxyadenosine 5′-monophosphate (dAMP) is incorporated into Caco-2 cells in a time-dependent manner. The uptake of 2′-Deoxyadenosine 5′-monophosphate is increased with a drop in pH, suggesting that 2′-Deoxyadenosine 5′-monophosphate transport activity might be linked to the protons. 2′-Deoxyadenosine 5′-monophosphate uptake by Caco-2 cells is pH- and Na+-dependent.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    ROS|P450|Trypsin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2922-74-9
  • Formula Weight
    375.188
  • Molecular Formula
    C10H12N5Na2O6P
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (266.53 mM)
  • SMILES
    [Na+].[Na+].Nc1ncnc2n(cnc12)C1CC(O)C(COP([O-])([O-])=O)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Biskup E, et al. Triterpenoid α-amyrin stimulates proliferation of human keratinocytes but does not protect them against UVB damage. Acta Biochim Pol. 2012;59(2):255-60. Epub 2012 May 11.
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